TargetMol

Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc

Product Code:
 
TAR-T41023
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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Further Information

Bioactivity:
Me-triacetyl-β-D-glucopyranuronate-Ph-CH2OH-Fmoc is a cleavable linker compound employed for the synthesis of antibody-drug conjugates (ADCs).
CAS:
894096-02-7
Molecular Weight:
748.738
Purity:
0.98
SMILES:
COC(=O)[C@H]1O[C@@H](Oc2ccc(CO)cc2NC(=O)CCNC(=O)OCC2c3ccccc3-c3ccccc23)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O

References

Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.