TargetMol

Orotic acid monohydrate

Product Code:
 
TAR-T5078
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T5078-100mg100mgEnquire
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Further Information

Bioactivity:
Orotic acid is an intermediate product in pyrimidine metabolism.
CAS:
50887-69-9
Molecular Weight:
174.11
Pathway:
Metabolism|Others
Purity:
1
SMILES:
O.OC(=O)c1cc(=O)[nH]c(=O)[nH]1
Target:
Endogenous Metabolite|Others

References

Jung, E.J., et al, Proliferating effect of orotic acid through mTORC1 activation mediated by negative regulation of AMPK in SK-Hep1 hepatocellular carcinoma cells. J Toxicol Sci, 2012. 37(4): p. 813-21. Manjeshwar, S., et al., The regulation of ribonucleoside diphosphate reductase by the tumor promoter orotic acid in normal rat liver in vivo. Mol Carcinog, 1999. 24(3): p. 188-96. Jung, E.J., et al., Role of the AMPK/SREBP-1 pathway in the development of orotic acid-induced fatty liver. J Lipid Res, 2011. 52(9): p. 1617-25.