TargetMol

Cilengitide TFA

Product Code:
 
TAR-T6806
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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TAR-T6806-100mg100mgEnquire
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TAR-T6806-500mg500mgEnquire
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Further Information

Bioactivity:
Cilengitide is a potent integrin inhibitor for αvβ3 receptor and αvβ5 receptor with IC50 of 4.1 nM and 79 nM in cell-free assays, respectively; ~10-fold selectivity against gpIIbIIIa. Phase 2.
CAS:
199807-35-7
Molecular Weight:
702.68
Pathway:
Autophagy|Cytoskeletal Signaling
Purity:
0.98
SMILES:
OC(=O)C(F)(F)F.CC(C)[C@@H]1N(C)C(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CCCNC(N)=N)NC1=O
Target:
Autophagy|Integrin

References

Nisato RE, et al. Angiogenesis, 2003, 6(2), 105-119. Oliveira-Ferrer L, et al. J Exp Clin Cancer Res, 2008, 27:86. Reardon DA, et al. Genes Cancer, 2011, 2(12):1159-1165.