TargetMol

SB-277011 hydrochloride

Product Code:
 
TAR-T63096
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20°C
1 / 1
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CodeSizePrice
TAR-T63096-500mg500mg£1,530.00
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This product comes from: United States.
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Further Information

Bioactivity:
SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally active, dopamine D3 receptor (D3R) antagonist that crosses the blood-brain barrier with Ki values of 10.7 nM and 11.2 nM for rodent and human D3R, respectively. 277011 hydrochloride is 80-100 times more selective for D3 receptors than other dopamine receptors, acting on D3 receptors (pKi:8.0), D2 receptors (pKi:6.0), 5-HT1B receptors (pKi<5.2) and 5-HT1D receptors (pKi:5.9).
CAS:
215804-67-4
Molecular Weight:
475.03
Purity:
0.98
SMILES:
Cl.O=C(N[C@H]1CC[C@H](CCN2CCc3cc(ccc3C2)C#N)CC1)c1ccnc2ccccc12