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JaICA

anti-4-Hydroxy-2-hexenal [4-HHE], mAb (HHE53)

Product Code:
 
JAI-MHH-030N
Product Group:
 
Primary Antibodies
Supplier:
 
JaICA
Antibody Isotype:
 
Mouse IgG1kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
HHE53
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Immunohistochemistry (IHC)
Shipping:
 
BLUE ICE
Storage:
 
-20°C
 

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JAI-MHH-030N-30ug30 ug£971.00
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This product comes from: Switzerland.
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Further Information

EClass:
32160000
Form (Short):
liquid
Formulation:
Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA.
Handling Advice:
Avoid freeze/thaw cycles.
Immunogen:
HHE-modified keyhole-lympet hemocyanine.
Long Description:
Monoclonal Antibody. Recognizes HHE-modified proteins (especially HHE-His Michael adducts). Frozen liquid. Contains 10mM PBS, 0.1% NaN3 and 0.5% BSA. 4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts.
Package Type:
Plastic Vial
Product Description:
4-hydroxy-2-alkenal is one of the major lipid peroxidation products, and shows many biological effects such as high toxicity to cells. Among them, 4-hydroxy-2-hexenal (HHE) is an aldehyde formed during peroxidation of n-3 fatty acids such as docosahexaenoic acid. HHE is highly reactive aldehyde and reacts with histidine residue of protein to form Michael-addition type adducts.
Source / Host:
Ascites
Specificity:
Recognizes HHE-modified proteins (especially HHE-His Michael adducts).
Transportation:
Non-hazardous
UNSPSC Category:
Primary Antibodies
UNSPSC Number:
12352203
Use & Stability:
Stable for at least 3 years after receipt when stored at -20°C.

References

Protein-bound 4-hydroxy-2-hexenal as a marker of oxidized n-3 polyunsaturated fatty acids: S. Yamada, et al.; J. Lipid. Res. 45, 626 (2004) | Accumulation of protein-bound 4-hydroxy-2-hexenal in spinal cords from patients with sporadic amyotrophic lateralsclerosis: N. Shibata, et al.; Brain Res. 1019, 170 (2004)