SAG Analog (LowTox)

Product Code:

AG-CR1-3517

Regulatory Status:

RUO

Shipping:

-20°C

Storage:

-20°C

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Code	Size	Price

AG-CR1-3517-M001

1 mg

£200.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Alternate Names/Synonyms:

Compound 10c; 3,4-Dichloro-N-(trans-4-(methylamino)cyclohexyl)-N-(3-pyridin-4-ylbenzyl)benzo[b]thiophene-2-carboxamide

Appearance:

White to light yellow solid.

CAS:

1401532-78-2

EClass:

32160000

Form (Short):

solid

Handling Advice:

Protect from light.

InChi:

InChI=1/C28H27Cl2N3OS/c1-31-21-8-10-22(11-9-21)33(17-18-4-2-5-20(16-18)19-12-14-32-15-13-19)28(34)27-26(30)25-23(29)6-3-7-24(25)35-27/h2-7,12-16,21-22,31H,8-11,17H2,1H3/t21-,22-

InChiKey:

OBYJCKCGYTYXFN-HZCBDIJEBZ

Long Description:

Chemical. CAS: 1401532-78-2. Formula: C28H27Cl2N3OS (trans-isomer). MW: 524.5. Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

MDL:

N/A

Molecular Formula:

C28H27Cl2N3OS (trans-isomer)

Molecular Weight:

524.5

Package Type:

Vial

Product Description:

Cell permeable low toxicity Sonic hedgehog (Shh) agonist. Cell permeable smoothened (Smo) agonist. Potent activator of VEGF expression in vitro.

Purity:

>98% (NMR)

SMILES:

[H][C@@]1(CC[C@@]([H])(CC1)N(CC1=CC=CC(=C1)C1=CC=NC=C1)C(=O)C1=C(Cl)C2=C(Cl)C=CC=C2S1)NC

Solubility Chemicals:

Soluble in DMSO.

Transportation:

Non-hazardous

UNSPSC Category:

Biochemical Reagents

UNSPSC Number:

12352200

Use & Stability:

Stable for at least 2 years after receipt when stored at -20°C. Store solutions at -20°C in the dark.

Documents

References

Potent small molecule Hedgehog agonists induce VEGF expression in vitro: K. Seifert, et al.; Bioorg. Med. Chem. 20, 6465 (2012)