AdipoGen Life Sciences

FGF-2 (human) (rec.)

Product Code:
 
AG-40T-0040
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
+4°C
 

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CodeSizePrice
AG-40T-0040-C01010 ug£110.00
Quantity:
AG-40T-0040-C05050 ug£225.00
Quantity:
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This product comes from: Switzerland.
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Further Information

Alternate Names/Synonyms:
Basic Fibroblast Growth Factor; bFGF; Heparin Binding Growth Factor-2; HBGF-2
Biological Activity:
The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by human FGF-2 (basic) has been determined to be in the range of 0.1-2 ng/ml.
EClass:
32160000
Endotoxin:
<0.1ng/µg protein.
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Long Description:
Protein. Human FGF-2 (153aa). Source: E. coli. Endotoxin content: <0.1ng/µg protein. Lyophilized. Contains PBS. Purity: >98% (SDS-PAGE). FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.
Molecular Weight:
~16.5kDa
NCBI, Uniprot Number:
P09038
Package Type:
Plastic Vial
Product Description:
FGF-2 plays an important role in the regulation of angiogenesis, cell survival, cell division, wound healing and tissue repair, embryonic development, cell differentiation and cell migration, neuronal function and neural degeneration. It functions as potent mitogen in vitro.
Purity:
>98% (SDS-PAGE)
Sequence:
Human FGF-2 (153aa).
Source / Host:
E. coli
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.

References

Loss of Akt activity increases circulating soluble endoglin release in preeclampsia: identification of inter-dependency between Akt-1 and heme oxygenase-1: M.J. Cudmore, et al.; Europ. Heart J. 33, 1150 (2012) | Endothelial Heparan Sulfate 6-O-sulfation Levels Regulate Angiogenic Responses of Endothelial Cells to FGF2 and VEGF: C. Ferreras, et al.; J. Biol. Chem. 287, 36132 (2012)