EGFR Soluble (human) (rec.)
Product Code:
AG-40T-0041
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This product comes from:
Switzerland.
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7-10 working days.
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Further Information
Alternate Names/Synonyms:
Epidermal Growth Factor Receptor; ERBB1; HER1
32160000
solid
Lyophilized.
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.
Protein. Human EGFR (629aa) is fused at the C-terminus to a Strep-tag. Source: Sf9 cells. Lyophilized. Purity: >90% (SDS-PAGE). EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
~85kDa
P00533
Plastic Vial
EGFR has been shown to bind a subset of the EGF family ligands, including EGF, amphiregulin, TGF-alpha, betacellulin, epiregulin, heparin-binding EGF and neuregulin-2 in the absence of a co-receptor. Ligand binding induces EGFR homodimerization as well as heterodimerization with ErbB2, resulting in kinase activation, tyrosine phosphorylation and cell signaling. EGFR signaling has been shown to regulate multiple biological functions including cell proliferation, differentiation, motility and apoptosis. In addition, EGFR signaling has also been shown to play a role in carcinogenesis.
>90% (SDS-PAGE)
Human EGFR (629aa) is fused at the C-terminus to a Strep-tag.
Sf9 cells
Strep
Non-hazardous
Other Proteins
12352202
Stable for at least 6 months after receipt when stored at -20°C.