AdipoGen Life Sciences

VEGF 165 (human) (rec.)

Product Code:
 
AG-40T-0043
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
+4°C
 

No additional charges, what you see is what you pay! *

CodeSizePrice
AG-40T-0043-C0055 ug£155.00
Quantity:
AG-40T-0043-C02020 ug£360.00
Quantity:
Prices exclude any Taxes / VAT
How to order with us   Contact us
Stay in control of your spending. These prices have no additional charges, not even shipping!
* Rare exceptions are clearly labelled (only 0.14% of items!).
Multibuy discounts available! Contact us to find what you can save.
This product comes from: Switzerland.
Typical lead time: 7-10 working days.
Contact us for more accurate information.
  • Further Information
  • Documents
  • References
  • Show All

Further Information

Alternate Names/Synonyms:
Vascular Endothelial Growth Factor; VEGF-A; VPF
Biological Activity:
The ED50 for stimulation of cell proliferation in human umbilical vein endothelial cells by VEGF 165 has been determined to be in the range of 1-5ng/ml.
EClass:
32160000
Endotoxin:
<0.1ng/µg protein.
Form (Short):
liquid
Formulation:
Lyophilized.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.For long term storage we recommend to add at least 0.1% human or bovine serum albumin.
Long Description:
Protein. Human VEGF 165 (165aa). Source: E. coli. Endotoxin content: <0.1ng/µg protein. Lyophilized. Purity: >95% (SDS-PAGE). Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
Molecular Weight:
~38.2kDa
NCBI, Uniprot Number:
P15692-4
Package Type:
Plastic Vial
Product Description:
Human vascular endothelial growth factor (VEGF 165) is produced as a homodimer. It binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. VEGF 165 is a specific mitogen for vascular endothelial cells and a strong angiogenic factor in vivo. In addition to its action as a mitogen it is a potent vascular permeability factor (VPF) in vivo. It is also a chemoattractant molecule for monocytes and endothelial cells. It induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels.
Purity:
>95% (SDS-PAGE)
Sequence:
Human VEGF 165 (165aa).
Source / Host:
E. coli
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C.

References

Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling: N.M.S. van den Akker, et al.; Cardiovasc. Res. 78, 366 (2008)