ProSci

NALP14 Antibody

Product Code:
 
PSI-5975
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
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Western blot analysis of NALP14 in rat brain tissue lysate with NALP14 antibody at 1 μg/mL.

Western blot analysis of NALP14 in rat brain tissue lysate with NALP14 antibody at 1 μg/mL.

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CodeSizePrice
PSI-5975-0.02mg0.02mg£150.00
Quantity:
PSI-5975-0.1mg0.1mg£449.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
NALP14 Antibody: NOD5, PAN8, GC-LRR, NALP14, CLR11.2, NOD5, NACHT, LRR and PYD domains-containing protein 14, Nucleotide-binding oligomerization domain protein 5
Application Note:
NALP14 antibody can be used for detection of NALP14 by Western blot at 1 μg/mL.

Antibody validated: Western Blot in rat samples. All other applications and species not yet tested.
Background:
NALP14 Antibody: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.
Background References:
  • Tschopp J, Martinon F, and Burns K. NALPs: a novel protein family involved in inflammation. Nat. Rev. Mol. Cell Biol.2003; 4:95-104.
  • Tian X, Pascal G, and Monget P. Evolution and functional divergence of NLRP genes in mammalian reproductive system. BMC Evol. Biol.2009; 9:202.
  • Westerveld GH, Korver CM, van Pelt AMM, et al. Mutations in the tesits-specific NALP14 gene in men suffering from spermatogenic failure. Hum. Reprod.2006; 21:3178-84.
Buffer:
NALP14 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
NALP14 antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of human NALP14.

The immunogen is located within amino acids 200 - 250 of NALP14.
NCBI Gene ID #:
338323
NCBI Official Name:
NLR family, pyrin domain containing 14
NCBI Official Symbol:
NLRP14
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_789792
Protein GI Number:
28827813
Purification:
NALP14 Antibody is affinity chromatography purified via peptide column.
Research Area:
Innate Immunity
Swissprot #:
Q86W24
User NOte:
Optimal dilutions for each application to be determined by the researcher.