ProSci

Hantaan Virus Nucleocapsid Antibody

Product Code:
 
PSI-7689
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
 

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CodeSizePrice
PSI-7689-0.02mg0.02mg£150.00
Quantity:
PSI-7689-0.1mg0.1mg£449.00
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Further Information

Additional Names:
Hantaan Virus Nucleocapsid Antibody: Nucleoprotein, Nucleocapsid protein, Protein N
Application Note:
Hantaan virus nucleocapsid antibody can detect 10ng Hantaan virus nucleocapsid peptide in ELISA at 1 μg/ml.
Background:
Hantaan virus (HNTV) is the prototype virus of the genus hantavirus of the family Bunyaviridae, an enveloped, negative-sense RNA virus that is the eiological agent of Korean hemorrhagic fever (1). Infection of cultured Vero E6 cells with HNTV induced expression of the heat shock protein HSP70. A substantial fraction of HSP70 was found to be associated with the HNTV nucleocapsid (NP) (2). Vero E6 cells that overexpress HSP70 show significantly reduced levels of NP and an increased resistance to infection by HNTV (2).
Background References:
  • Arikawa J, Lapenotiere HF, Iacono-Connors L, et al. Coding properties of the S and M genome segments of Sapporo rat virus: comparison to other causative agents of hemorrhagic fever with renal syndrome. Virology 1990; 176:114-25.
  • Yu L, Ye L, Zhao R, et al. HSP70 induced by Hantavirus intfection interacts with viral nucleocapsid protein and its overexpression suppresses virus infection in Vero E6 cells. Am. J. Transl. Res. 2009; 1:367-80.
Buffer:
Hantaan virus nucleocapsid antibody is supplied in PBS containing 0.02% sodium azide.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Hantaan virus nucleocapsid antibody was raised against an 18 amino acid peptide near the amino terminus of the Hantaan virus nucleocapsid.

The immunogen is located within the first 50 amino acids of Hantaan Virus Nucleocapsid.
NCBI Gene ID #:
2943078
NCBI Official Name:
HTNVsSgp1 nucleocapsid protein
NCBI Official Symbol:
HTNVsSgp1
NCBI Organism:
Hantaan virus
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
N/A
Protein Accession #:
AFA36178
Protein GI Number:
375127553
Purification:
Hantaan virus nucleocapsid antibody is affinity chromatography purified via peptide column.
Research Area:
Infectious Disease
Swissprot #:
P05133
User NOte:
Optimal dilutions for each application to be determined by the researcher.