Further Information
THRA, thyroid hormone receptor, alpha (erythroblastic leukemia viral (v-erb-a) oncogene homolog, avian), AR7, EAR7, ERB-T-1, ERBA, ERBA1, MGC000261, MGC43240, NR1A1, THRA1, THRA2, c-ERBA-1, ERBA-related 7, avian erythroblastic leukemia viral (v-erb-a) oncogene homolog, thyroid hormone receptor, alpha, triiodothyronine receptor
Peptide ELISA: antibody detection limit dilution 1:32000.Western Blot:Approx 60+50kDa bands observed in Human Bone Marrow lysates (calculated MW of 54.8kDa according to NP_003241.2 and of 46.8kDa according to NP_955366.1). Recommended concentration: 0.5-1ug/ml. Primary incubation was 1 hour.Immunohistochemistry:Paraffin embedded Human Tonsil and Breast. Recommended concentration: 3.75ug/ml.
- Nishiyama K, Baba S, Yamada T, Matsushita A, Natsume H, Nakano K, Sasaki S, Nakamura H. Embryonic lethal effect of expressing a dominant negative mutant human thyroid hormone receptor alpha1 in mice. Endocr J. 2003 Oct;50(5):561-70.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Mouse, Rat, Dog, Pig, Cow
The immunogen for this antibody is: C-KEEMIRSLQQRP
7067
thyroid hormone receptor, alpha
THRA
Homo sapiens
Liquid
NP_955366.1, NP_003241.2
40806160
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Cancer
This antibody is expected to recognize both reported isoforms (NP_955366.1; NP_003241.2). This antibody is not expected to cross-react to THRB.
P10827