ProSci

CCR5 Antibody

Product Code:
 
PSI-79-765
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20˚C for up to one year.
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Western blot analysis of lysed extracts from Mouse liver tissue using CCR5 (CD195).
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Western blot analysis of lysed extracts from Mouse liver tissue using CCR5 (CD195).

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PSI-79-765-0.1mg0.1mg£481.00
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Further Information

Additional Names:
CKR5, CCR-5, CD195, CKR-5, CCCKR5, CMKBR5, IDDM22, CC-CKR-5, CREB2, CREBP1, CKR5
Application Note:
Western Blot: 1:500~1:1000
Background:
Receptor for a number of inflammatory CC-chemokines including MIP-1-alpha, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Background References:
  • Samson M., Labbe O., Mollereau C., Vassart G., Parmentier M. Biochemistry 35:3362-3367 (1996) Raport C. J., Gosling J., Schweichart V. L., Gray P. W., Charo I. F. J. Biol. Chem. 271:17161-17166 (1996) Combadiere C., Ahuja S. K., Tiffany H. L., Murphy P. M. J. Leukoc. Biol. 60:147-152 (1996)
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CCR5 (CD195) antibody was raised against a peptide sequence around aa.11~15 (D-I-N-Y-Y) derived from Human CCR5 (CD195).
NCBI Gene ID #:
1234
NCBI Official Name:
chemokine (C-C motif) receptor 5 (gene/pseudogene)
NCBI Official Symbol:
CCR5
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
41 kDa
Protein Accession #:
NP_000570.1
Protein GI Number:
4502639
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Other
SPECIFICITY:
This antibody detects endogenous level of total CCR5(CD195) protein.
Swissprot #:
P51681