Antibody Clonality:
Polyclonal
Target Species:- Canine (dog)
- Fish
- Human
- Mouse
- Rat
Applications:- Enzyme-Linked Immunosorbent Assay (ELISA)
- Western Blot (WB)
Storage:
For short periods of storage (days) store at 4˚C. For longer periods of storage, store NR2F2 antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
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This product comes from:
United States.
Typical lead time:
14-21 working days.
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Further Information
NR2F2, ARP1, NF-E3, NR2F1, SVP40, COUPTFB, TFCOUP2, COUPTFII
NR2F2 antibody can be used for detection of NR2F2 by ELISA at 1:1562500. NR2F2 antibody can be used for detection of NR2F2 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
NR2F2, an orphan member of the nuclear hormone receptor superfamily, acts as a transcriptional repressor by antagonizing the functions of other nuclear hormone receptors and by actively silencing transcription. However, in certain contexts, NR2F2 stimulates transcription directly. NR2F2, MyoD and p300 interact in a competitive manner, and that increasing amounts of NR2F2 have the ability to reduce the interaction between myoD and p300 invitro. NR2F2 post-transcriptionally regulates myoD activity/function, and that crosstalk between orphan nuclear receptors and the myogenic bHLH proteins has functional consequences for differentiation.
- Sato, Y., et al., (2003) J. Clin. Endocrinol. Metab. 88 (7), 3415-3420.
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
batch dependent
Unconjugated
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NR2F2.
7026
nuclear receptor subfamily 2, group F, member 2
NR2F2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
46 kDa
NP_066285
14149746
Antibody is purified by protein A chromatography method.
Transcription ,Cancer
P24468
Optimal dilutions for each application to be determined by the researcher.