Further Information
HB16, CREB2, TREB7, CREB-2, CRE-BP1, JNK1, PRKM8, SAPK1, SAPK1C, CREBP1
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200
Transcriptional activator, probably constitutive, which binds to the cAMP-responsive element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Interaction with JUN redirects JUN to bind to CRES preferentially over the 12-O-tetradecanoylphorbol-13-acetate response elements (TRES) as part of an ATF2-c-Jun complex.
- Sevilla A, et al. (2004) J Biol Chem. 279 (26): 27458-27465. Sakurai A, et al. (1991) Biochem Biophys Res Commun. 181 (2): 629-635. Abdel-Hafiz H A, et al. (1992) Mol Endocrinol. 6: 2079-2089. Gupta S, et al. (1995) Science. 267: 389-393. Van Dam H, et al. (1995) EMBO J. 14 (8): 1798-1811.
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
1 mg/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
ATF2 (Ab-62 or 44) antibody was raised against a peptide sequence around aa.serine 60~64 or 42~46 (N-D-S-V-I) derived from Human ATF2.
1386
activating transcription factor 2
ATF2
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
65 - 75 kDa
NP_001871.2
22538422
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Other
This antibody detects endogenous level of total ATF-2 protein.
P15336