ProSci

GSN Antibody

Product Code:
 
PSI-26-845
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
For short periods of storage (days) store at 4˚C. For longer periods of storage, store GSN antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
1 / 3
Antibody used in WB on Human MCF7 at 0.2-1 ug/ml.
2 / 3
3 / 3
Antibody used in IHC on Human Tonsil at of 5 ug/ml.
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Antibody used in WB on Human MCF7 at 0.2-1 ug/ml.
Antibody used in IHC on Human Tonsil at of 5 ug/ml.

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PSI-26-845-100ul100ul£662.00
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Further Information

Additional Names:
GSN, DKFZp313L0718, ADF, AGEL
Application Note:
GSN antibody can be used for detection of GSN by ELISA at 1:62500. GSN antibody can be used for detection of GSN by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Background:
GSN binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. It is a calcium-regulated protein, which functions in both assembly and disassembly of actin filaments. Defects in the gene encoding GSN are a cause of familial amyloidosis Finnish type (FAF).The protein encoded by this gene binds to the 'plus' ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.
Background References:
  • Shokouhi, G. Nephrol. Dial. Transplant. 23 (3), 1071 (2008).
Buffer:
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human GSN.
NCBI Gene ID #:
2934
NCBI Official Name:
gelsolin
NCBI Official Symbol:
GSN
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
83 kDa
Protein Accession #:
NP_000168
Protein GI Number:
4504165
Purification:
Antibody is purified by peptide affinity chromatography method.
Research Area:
Cancer ,Signal Transduction
Swissprot #:
P06396
User NOte:
Optimal dilutions for each application to be determined by the researcher.