ProSci

NAT2 Antibody

Product Code:
 
PSI-46-943
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Caprine (Goat)
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Enzyme-Linked Immunosorbent Assay (ELISA)
Storage:
 
Aliquot and store at -20˚C. Minimize freezing and thawing.
 

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CodeSizePrice
PSI-46-943-0.1mg0.1mg£505.00
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Further Information

Additional Names:
NAT2 , N-acetyltransferase 2 (arylamine N-acetyltransferase) , AAC2, Arylamine N-acetyltransferase-2, arylamide acetylase 2, arylamide acetylase 2 (N-acetyltransferase 2, isoniazid inactivation), arylamine N-acetyltransferase 2
Application Note:
Peptide ELISA: antibody detection limit dilution 1:16000.Western Blot:Preliminary experiments gave an approx 27 kDa band in Human Kidney, Liver and Testis lysates after 1ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 33.6 kDa according to NP_000006.2. The 27 kDa band was successfully blocked by incubation with the immunizing peptide. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates? Have any further splice variants/modified forms been reported?
Background References:
  • Wu H, Dombrovsky L, Tempel W, Martin F, Loppnau P, Goodfellow GH, Grant DM, Plotnikov AN. Structural basis of substrate-binding specificity of human arylamine N-acetyltransferases. J Biol Chem. 2007 Oct 12;282(41):30189-97. Epub 2007 Jul 26.
Buffer:
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20?C. Minimize freezing and thawing.
Concentration:
500 ug/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Homology:
Expected Species Reactivity based on sequence homology: Human
Immunogen:
The immunogen for this antibody is: C-PKKKHQKIYLFTLE
NCBI Gene ID #:
10
NCBI Official Name:
N-acetyltransferase 2 (arylamine N-acetyltransferase)
NCBI Official Symbol:
NAT2
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
NP_000006.2
Protein GI Number:
116295260
Purification:
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Research Area:
Cancer
Swissprot #:
P11245