Further Information
ABCA2, ATP-binding cassette, sub-family A (ABC1), member 2, ABC2, MGC129761, ATP-binding cassette, sub-family A, member 2, OTTHUMP00000064733
Peptide ELISA: antibody detection limit dilution 1:2000.Western Blot:Preliminary experiments gave an approx 35kDa band in Human Brain (Amygdala, Frontal Cortex, Hippocampus and Substantia Nigra) lysates after 0.3ug/ml antibody staining. Please note that currently we cannot find an explanation in the literature for the band we observe given the calculated size of 270kDa according to NP_001597.2 and of 273kDa according to .NP_997698.1. The 35kDa band was successfully blocked by incubation with the immunizing peptide.Immunohistochemistry:Paraffin embedded Human Brain (Cortex). Recommended concentration: 3.75ug/ml.
- Mace S, Cousin E, Ricard S, Genin E, Spanakis E, Lafargue-Soubigou C, Genin B, Fournel R, Roche S, Haussy G, Massey F, Soubigou S, Brefort G, Benoit P, Brice A, Campion D, Hollis M, Pradier L, Benavides J, Deleuze JF ABCA2 is a strong genetic risk factor for early-onset Alzheimer's disease Neurobiol Dis. 2005 Feb;18(1):119-25
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Mouse, Rat
The immunogen for this antibody is: C-KKQSDNLEQQETEP
20
ATP-binding cassette, sub-family A (ABC1), member 2
ABCA2
Homo sapiens
Liquid
NP_001597.2, NP_997698.1
45446740
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Signal Transduction ,Neuroscience ,Obesity ,Immunology
This antibody is expected to recognize both reported isoforms (NP_001597.2; NP_997698.1).
Q9BZC7