Chemodex

N-Octanoyl-L-homoserine lactone

Product Code:
 
CDX-O0038
Product Group:
 
Other Biochemicals
Supplier:
 
Chemodex
Regulatory Status:
 
RUO
Shipping:
 
AMBIENT
Storage:
 
+4°C
1 / 1
Chemical Structure
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Chemical Structure

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CDX-O0038-M0055 mg£72.00
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CDX-O0038-M05050 mg£377.00
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Further Information

Alternate Names/Synonyms:
N-[(3S)-Tetrahydro-2-oxo-3-furanyl]-octanamide; C8-HSL; OHL
Appearance:
White powder.
CAS:
147852-84-4
EClass:
32160000
Form (Short):
liquid
Handling Advice:
Keep cool and dry.Protect from light and moisture.
InChi:
InChI=1S/C12H21NO3/c1-2-3-4-5-6-7-11(14)13-10-8-9-16-12(10)15/h10H,2-9H2,1H3,(H,13,14)/t10-/m0/s1
InChiKey:
JKEJEOJPJVRHMQ-JTQLQIEISA-N
Long Description:
Chemical. CAS: 147852-84-4. Formula: C12H21NO3. MW: 227.3. Synthetic. N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.
MDL:
MFCD11113139
Molecular Formula:
C12H21NO3
Molecular Weight:
227.3
Package Type:
Vial
Product Description:
N-Octanoyl-L-homoserine lactone (C8-HSL) is a small diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and affecting cellular metabolism. The applications of this molecule include infection prevention and regulation of virulence in general and in cystic fibrosis.
Purity:
>98% (NMR)
SMILES:
CCCCCCCC(=O)N[C@H]1CCOC1=O
Solubility Chemicals:
Soluble in DMSO and dimethylformamide (approx. 30mg/ml).
Source / Host:
Synthetic.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at +4°C.

References

(1) J.T. Hodgkinson; Tetrahedron Lett. 52, 3291 (2011) | (2) G.D. Geske; JACS 127, 12762 (2005) | (3) A. Kuo, et al.; J. Bacteriol. 176, 7558 (1994) | (4) J.K. Lithgow, et al.; Mol. Microbiol. 37, 81 (2000) | (5) K.H. McClean, et al.; Microbiol. 143, 3703 (1997) | (6) K. Riedel, et al.; Microbiol. 147, 3249 (2001) | (7) M.K. Winson, et al.; PNAS 92, 9427 (1995)