ProSci

PARK2 Peptide

Product Code:
 
PSI-7903P
Product Group:
 
Peptides
Supplier:
 
ProSci
Antibody Clone:
 
169790969
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Bl
Storage:
 
Store PARK2 Peptide at -20˚C, stable for one year.
 

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CodeSizePrice
PSI-7903P-0.05mg0.05mg£166.00
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Further Information

Additional Names:
PDJ, PRKN, AR-JP, LPRS2, E3 ubiquitin-protein ligase parkin, Parkinson juvenile disease protein 2, Parkinson disease protein 2
Application Note:
The peptide is used for blocking the activity of PARK2 Antibody (catalog number 7903). It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37˚C.
Background References:
  • Dauer W and Przedborski S. Parkinson?s disease: Mechanisms and models. Neuron 2003; 39:889-909.
  • Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998; 392:605-8.
  • Shimura H, Hattori N, Kubo Si, et al. Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase. Nat. Genet. 2000; 25:302-5.
  • Johnson BN, Berger AK, Cortese GP, et al. The ubiquitin E3 ligase parkin regulates the proapoptotic function of Bax. Proc. Natl. Acad. Sci. USA 2012; 109:6283-88.
Buffer:
PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide
Concentration:
200 ug/mL
NCBI Gene ID #:
5071
NCBI Official Name:
parkin RBR E3 ubiquitin protein ligase
NCBI Official Symbol:
PARK2
NCBI Organism:
homo sapiens
Peptide aa Location:
17 amino acids near the amino terminus of human PARK2.
Physical State:
Liquid
Protein Accession #:
NP_004553
Protein GI Number:
169790969
Swissprot #:
O60260

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