ProSci

KMO Antibody

Product Code:
 
PSI-39-869
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
 

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PSI-39-869-0.1mg0.1mg£782.00
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Further Information

Additional Names:
317G22.1, KMO_HUMAN, Kynurenine 3 hydroxylase, Kynurenine 3 monooxygenase (kynurenine 3 hydroxylase), Kynurenine 3 monooxygenase, Kynurenine 3-hydroxylase, Kynurenine 3-monooxygenase, RP1-317G22.1, AI046660,
Application Note:
ELISA, Western (immuno) blotting, Immunostaining (in testing)
Background:
Kynurenine 3-monooxygenase (KMO) catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). The enzyme is required for synthesis of quinolinic acid. Quinolinic acid ia a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development.
Background References:
  • Eniko Vamosa, Arpad Pardutza, Peter Klivenyia, Jozsef Toldib and Laszlo Vecsei, The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection. 2009 Journal of the Neurological Sciences Article in Press, Corrected Proof available on line
Concentration:
batch dependent
Conjugate:
Unconjugated
Immunogen:
A synthetic peptide corresponding to an internal region between amino acids 200-299.
NCBI Gene ID #:
98256
NCBI Official Name:
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
NCBI Official Symbol:
APP
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
EDL13209
Protein GI Number:
81879610
Purification:
Affinity Purified
Research Area:
Cancer
Swissprot #:
Q91WN4
User NOte:
Optimal dilutions for each application to be determined by the researcher.