ProSci

IL-12 Recombinant Protein

Product Code:
 
PSI-40-520
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized IL-12 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-12 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

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CodeSizePrice
PSI-40-520-0.002mg0.002mg£300.00
Quantity:
PSI-40-520-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
CLMF, NKSF, CLMF2, NKSF2, IL-12B, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40 kDa subunit
Background:
IL-12 is a disulfide-linked heterodimeric protein (p70), composed of two subunits, p35 and p40, which are encoded by two different genes. Accumulating data indicate that p40 secretion precedes that of IL-12 expression. In addition, to its ability to covalently bind to p35 to form IL-12, p40 can bind to p19 to form IL-23, or can form a homodimer designated as IL-12 p80. Elevated levels of IL-12 p80 are correlated with macrophage recruitment and increased inflammation in asthma and respiratory viral infection models. Recombinant human IL-12 p80 is an 80.0 kDa disulfide linked homodimer consisting of two p40 chains of IL-12.
Biological Activity:
Endotoxin level is less than 0.1 ng per ug (1EU/μg).
NCBI Gene ID #:
3593
NCBI Official Name:
interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40)
NCBI Official Symbol:
IL12B
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_002178.2
Protein GI Number:
24497438
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.
Recombinant Protein Sequence:
#N/A
Source:
(BTI-Tn-5B1-4) High-5 Insect cells
Swissprot #:
P29460

Documents