ProSci

IL-12 Recombinant Protein

Product Code:
 
PSI-40-255
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized IL-12 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IL-12 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, expos
 

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CodeSizePrice
PSI-40-255-0.002mg0.002mg£300.00
Quantity:
PSI-40-255-0.01mg0.01mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
P35, CLMF, NFSK, NKSF1, IL-12A, Interleukin-12 subunit alpha, Cytotoxic lymphocyte maturation factor 35 kDa subunit
Background:
IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-γ producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues).
Biological Activity:
The ED50 was determined by the induction of IFN - gamma from NK cells co - stimulated with IL - 18 is ≤ 1.0 ng/mL, corresponding to a specific activity of ≥ 1 x 106 units/mg.
NCBI Gene ID #:
3592
NCBI Official Name:
interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35)
NCBI Official Symbol:
IL12A
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_000873.2
Protein GI Number:
24430219
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P29459

Documents