ProSci

IFN beta Recombinant Protein

Product Code:
 
PSI-40-278
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized IFN beta recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted IFN beta is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein,
 

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CodeSizePrice
PSI-40-278-0.005mg0.005mg£300.00
Quantity:
PSI-40-278-0.02mg0.02mg£428.00
Quantity:
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Further Information

Additional Names:
IFB, IFF, IFNB, IFB, Interferon beta, Fibroblast interferon, IFN-beta
Background:
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell proliferation and modulate immune responses. Produced by peripheral blood leukocytes and lymphoblastoid cells, IFNα is an acid stable molecule that signals through IFNα/βR, which is also used by IFNβ. Both IFNs have similar anti-viral activity and regulate expression of MHC class I antigens. IFNα contains four highly conserved cysteine residues which form two disulfide bonds, one of which is necessary for biological activity. Recombinant human IFNβ is an 20.0 kDa protein containing 166 amino acid residues. Due to glycosylation, IFNβ has an approximate MW of 22.3 kDa based on SDS-PAGE gel and Mass Spectrometry.
Biological Activity:
Determined by a cytotoxicity assay using human TF-1 cells. The expected ED50 is < 0.1 ng/ml, corresponding to a specific activity of > 1 x 107units/mg.
NCBI Gene ID #:
3456
NCBI Official Name:
interferon, beta 1, fibroblast
NCBI Official Symbol:
IFNB1
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_002167.1
Protein GI Number:
4504603
Purity:
Greater than 95% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
CHO cells
Swissprot #:
P01574

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