ProSci

Midkine Recombinant Protein

Product Code:
 
PSI-40-504
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized Midkine recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Midkine is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protein, e
 

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CodeSizePrice
PSI-40-504-0.005mg0.005mg£300.00
Quantity:
PSI-40-504-0.02mg0.02mg£428.00
Quantity:
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
MK, ARAP, NEGF2, MK1, Midkine, Amphiregulin-associated protein, MK
Background:
Midkine (MK) and its functionally-related protein Pleiotrophin are heparin-binding neurotrophic factors that signal through the same receptor, known as anaplastic lymphoma kinase (ALK). MK plays an important regulatory role in epithelial-mesenchymal interactions during fetal development and in postnatal lung development. MK chemoattracts embryonic neurons, neutrophils and macrophages, and by signaling through the ALK receptor it exerts angiogenic, growth and survival activities during tumorgenesis. Recombinant human Midkine is a 13.4 kDa protein containing 123 amino acid residues including five intra-molecular disulfide bonds.
Biological Activity:
Biological activity was determined by its ability to chemoattract human neutrophils using a concentration range of 0.1 - 10.0 ng/mL.
NCBI Gene ID #:
4192
NCBI Official Name:
midkine (neurite growth-promoting factor 2)
NCBI Official Symbol:
MDK
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001012333.1
Protein GI Number:
59894796
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P21741

Documents