ProSci

TGF-alpha Recombinant Protein

Product Code:
 
PSI-40-117
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
The lyophilized TGF-alpha recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted TGF-alpha is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As with any protei
 

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CodeSizePrice
PSI-40-117-0.02mg0.02mg£300.00
Quantity:
PSI-40-117-0.1mg0.1mg£428.00
Quantity:
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Further Information

Additional Names:
TFGA, Protransforming growth factor alpha, EGF-like TGF, TGF-alpha
Background:
TGF-α is an EGF-related polypeptide growth factor that signals through the EGF receptor, and stimulates the proliferation of a wide range of epidermal and epithelial cells. It is produced by monocytes, keratinocytes, and various tumor cells. TGF-α induces transformation anchorage independence in cultured cells. Human, murine and rat TGF-α are cross-species reactive. Recombinant human TGF-α is a 50 amino acid polypeptide (5.5 kDa) which shares approximately 40% sequence homology with EGF, including 6 conserved cysteine residues, which form 3 intramolecular disulfide bonds.
Biological Activity:
The ED50 was determined by the dose - dependent stimulation of thymidine uptake by BALB/c 3T3 cells is ≤ 0.2 ng/mL, corresponding to a specific activity of ≥ 5 x 106 units/mg.
NCBI Gene ID #:
7039
NCBI Official Name:
transforming growth factor, alpha
NCBI Official Symbol:
TGFA
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
NP_001093161.1
Protein GI Number:
153791414
Purity:
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).
Recombinant Protein Sequence:
#N/A
Source:
E. coli
Swissprot #:
P01135

Documents