Cardiotrophin-1 Recombinant Protein

Product Code:

PSI-40-441

Product Group:

Recombinant Proteins

Supplier:

ProSci

Regulatory Status:

RUO

Target Species:

Mouse

Storage:

The lyophilized Cardiotrophin-1 recombinant protein is stable for at least 2 years from date of receipt at -20°C. Reconstituted Cardiotrophin-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. As wit

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Code	Size	Price

PSI-40-441-0.002mg

0.002mg

£300.00

Quantity:

PSI-40-441-0.01mg

0.01mg

£428.00

Quantity:

Prices exclude any Taxes / VAT

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Further Information

Additional Names:

CT-1, Cardiotrophin-1, CT-1

Background:

CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NNT-1/ BCSF-3. CT-1 is a pleiotropic cytokine which is expressed in various tissues including the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung and signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Recombinant murine Cardiotrophin-1 is a 21.3 kDa protein consisting of 202 amino acid residues.

Biological Activity:

The ED50 was determined by the dose - dependent proliferation of TF - 1 cells was < 1.0 ng/mL, corresponding to a specific activity of > 1 x 10⁶ units/mg.

NCBI Gene ID #:

13019

NCBI Official Name:

cardiotrophin 1

NCBI Official Symbol:

Ctf1

NCBI Organism:

Mus musculus

Physical State:

Lyophilized

Protein Accession #:

NP_031821.1

Protein GI Number:

6681075

Purity:

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μg (1EU/μg).

Recombinant Protein Sequence:

#N/A

Source:

E. coli

Swissprot #:

Q60753

Documents

Datasheet