ProSci

CD3 zeta (phospho Tyr142) Antibody

Product Code:
 
PSI-79-785
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from JK cells (Lane 2) and K562 cells (Lane 3), using CD3 ζ (Phospho-Tyr142) Antibody. The lane on the left is treated with antigen-specific peptide.
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Western blot analysis of extracts from JK cells (Lane 2) and K562 cells (Lane 3), using CD3 ζ (Phospho-Tyr142) Antibody. The lane on the left is treated with antigen-specific peptide.

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PSI-79-785-0.1mg0.1mg£488.00
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Further Information

Additional Names:
T3Z, CD3-zeta, TCRZ, T-cell receptor T3 zeta chain
Application Note:
Western Blot: 1:500~1:1000
Background:
Probable role in assembly and expression of the TCR complex as well as signal transduction upon antigen triggering.
Background References:
  • Linda A. Trimble, Blood, Aug 2000; 96: 1021 - 1029.
  • Sandeep Krishnan, J. Immunol., Sep 2005; 175: 3417 - 3423.
  • Linda A. Trimble, J. Virol., Aug 2000; 74: 7320 - 7330.
  • Hisashi Arase, J. Immunol., Jan 2001; 166: 21.
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
CD3 zeta (phospho Tyr142) antibody was raised against a peptide sequence around phosphorylation site of tyrosine 142 (G-L-Y (p)-Q-G) derived from Human CD3 ?.
Modifications:
Phospho-Specific
NCBI Gene ID #:
919
NCBI Official Name:
CD247 molecule
NCBI Official Symbol:
CD247
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
20 kDa
Protein Accession #:
NP_000725.1
Protein GI Number:
23830999
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of CD3 ? only when phosphorylated at tyrosine 142.
Swissprot #:
P20963