ProSci

IGFBP-3 (phospho Ser183) Antibody

Product Code:
 
PSI-80-047
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Application:
 
Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.
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Western blot analysis of extracts from Rat brain tissue using IGFBP-3 (Phospho-Ser183) Antibody. The lane on the right is treated with the antigen-specific peptide.

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PSI-80-047-0.1mg0.1mg£488.00
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Further Information

Additional Names:
IBP-3, IBP3, IGF-binding protein 3, IGFBP3, Insulin-like growth factor binding protein 3 precursor
Application Note:
Western Blot: 1:500~1:1000
Background:
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Background References:
  • Zhang Q, Steinle JJ (2013)Invest Ophthalmol Vis Sci 54, 3052-7 . Cobb LJ, Liu B, Lee KW, Cohen P (2006) Cancer Res 66, 10878-84 .
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
IGFBP-3 (phospho Ser183) antibody was raised against a peptide sequence around phosphorylation site of serine 183 (K-D-S (p)-Q-R) derived from Human IGFBP-3 .
Modifications:
Phospho-Specific
NCBI Gene ID #:
3486
NCBI Official Name:
insulin-like growth factor binding protein 3
NCBI Official Symbol:
IGFBP3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
30 kDa
Protein Accession #:
NP_000589.2
Protein GI Number:
62243248
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous level of IGFBP-3 only when phosphorylated at serine 183.
Swissprot #:
P17936