ProSci

Retinoblastoma (phospho Ser608) Antibody

Product Code:
 
PSI-79-834
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rabbit
Antibody Isotype:
 
IgG
Antibody Clonality:
 
Polyclonal
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Applications:
  • Immunohistochemistry (IHC)
  • Western Blot (WB)
Storage:
 
Store antibody at -20°C for up to one year.
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Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody. The lane on the left is treated with antigen-specific peptide.
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Immunohistochemical analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody (left) or the same antibody preincubated with blocking peptide (right).
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Western blot analysis of extracts from JK cells (Lane 2), using Retinoblastoma (Phospho-Ser608) Antibody. The lane on the left is treated with antigen-specific peptide.
Immunohistochemical analysis of paraffin-embedded human brain tissue using Retinoblastoma (Phospho-Ser608) antibody (left) or the same antibody preincubated with blocking peptide (right).

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PSI-79-834-0.1mg0.1mg£488.00
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Further Information

Additional Names:
P105-RB, PP105, PP110, RB1
Application Note:
Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
Background:
Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. Spontaneous regression ('cure') occurs in some cases.
Background References:
  • Lee W.-H., Nature 329:642-645(1987).
  • Lee W.-H., Science 235:1394-1399(1987).
  • Friend S.H., Proc. Natl. Acad. Sci. U.S.A. 84:9059-9063(1987).
Buffer:
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration:
1 mg/mL
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Retinoblastoma (phospho Ser608) antibody was raised against a peptide sequence around phosphorylation site of Serine 608 (Y-L-S (p)-P-V) derived from Human Retinoblastoma.
Modifications:
Phospho-Specific
NCBI Gene ID #:
5925
NCBI Official Name:
retinoblastoma 1
NCBI Official Symbol:
RB1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
PREDICTED MOLECULAR WEIGHT:
110 kDa
Protein Accession #:
NP_000312.2
Protein GI Number:
108773787
Purification:
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Research Area:
Phospho-Specific
SPECIFICITY:
The antibody detects endogenous levels of Retinoblastoma only when phosphorylated at serine 608.
Swissprot #:
P06400