ProSci

CD184 Antibody [2B11] (PE)

Product Code:
 
PSI-76-871
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Rat
Antibody Isotype:
 
Rat IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
2B11
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Flow Cytometry
Storage:
 
The product should be stored undiluted at 4°C and should be protected from prolonged exposure to light. Do not freeze.
 

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CodeSizePrice
PSI-76-871-0.1mg0.1mg£601.00
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Further Information

Additional Names:
CD184, LESTR, Sdf1r, Cmkar4, PB-CKR, b2b220Clo, PBSF/SDF-1
Background:
The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor. It is expressed by astrocytes, B cells, T cells, monocytes, neutrophils, neurons, and hematopoietic cell types. CD184 is a coreceptor for X4 HIV-1.The monoclonal 2B11 antibody recognizes the amino terminus of CD184 and has functional activity.
Background References:
  • Pierelli, L., Bonanno, G., Rutella, S., Marone, M., Scambia, G., Leone, G. (2001). CD105 (endoglin) expression on hematopoietic stem/progenitor cells.Leukemia lymphoma,42(6), 1195-1206.
  • She, X., Matsuno, F., Harada, N., Tsai, H., Seon, B. K. (2004). Synergy between antiendoglin (CD105) monoclonal antibodies and TGF-beta in suppression of growth of human endothelial cells.International journal of cancer,108(2), 251-257.
  • Seon, B. K., Kumar, S. (2002). CD105 antibody for targeting of tumor vascular endothelial cells. InThe new angiotherapy(pp. 499-515). Humana Press.
Buffer:
Phosphate-buffered aqueous solution, ?0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
Concentration:
batch dependent
Conjugate:
PE
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
NCBI Gene ID #:
12767
NCBI Official Name:
chemokine (C-X-C motif) receptor 4
NCBI Official Symbol:
Cxcr4
NCBI Organism:
Mus musculus
Physical State:
liquid
Purification:
The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.
Research Area:
Stem Cell,Chemokines & Cytokines, Growth Factors
SPECIFICITY:
The 2B11 monoclonal antibody specifically reacts with mouse CD184 (CXCR4or Fusin), a seven-transmembrane G-protein-coupled receptor.
Swissprot #:
P70658
User NOte:
Optimal dilutions for each application to be determined by the researcher.