ProSci

Glypican 3 Recombinant Protein

Product Code:
 
PSI-96-360
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-360-0.1mg0.1mg£686.00
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Further Information

Additional Names:
GPC3, OCI5, Glypican-3, GTR2-2, MXR7, DGSX, SDYS , SGB, SGBS, SGBS1
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Background References:
  • Davoodi J., et al., 2007, Proteomics 7:2300-2310.
  • Veugelers M., et al., 2000, Hum. Mol. Genet. 9:1321-1328.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized rh GPC3 / Glypican-3 at 5μg/ml (100μl/well) can bind human bFGF / FGF2 with a linear ranger of 0. 16 - 3. 2 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
2719
NCBI Official Name:
glypican 3
NCBI Official Symbol:
GPC3
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
61.7 kDa
Protein Accession #:
NP_004475
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P51654

Documents