ProSci

CD200 Recombinant Protein

Product Code:
 
PSI-96-573
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Applications:
  • Enzyme-Linked Immunosorbent Assay (ELISA)
  • Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-573-0.1mg0.1mg£597.00
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Further Information

Additional Names:
CD200, MOX1, MOX2, MRC, OX-2, My033
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
CD200 is also known as OX-2 membrane glycoprotein (OX-2), is a type-1 membrane glycoprotein, which contains two immunoglobulin domains (1 Ig-like C2-type (immunoglobulin-like) domain and Ig-like V-type (immunoglobulin-like) domain), and thus belongs to the immunoglobulin superfamily. CD200 / OX-2 is widely expressed in multiple cell types. CD200 interacts with a structurally related receptor (CD200R) expressed mainly on myeloid cells and is involved in regulation of macrophage and mast cell function. OX-2 / CD200 and CD200R associate via their respective N-terminal Ig-like domains. CD200 also plays an important role in prevention of graft rejection, autoimmune diseases and spontaneous abortion.
Background References:
  • McCaughan, G.W. et al., 1987, Immunogenetics 25:329-335.
  • Chen, Z. et al., 2006, Mol Immunol. 43 (6): 579-587.
  • Wright GJ., et al., 2003, J. Immunol. 171 (6): 3034?46.
Biological Activity:
Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD200R1 at 2μg/ml,the concentration of rhCD200 that produces 50% of the optimal binding response is appoximately 0. 5-16 ng/mL.
Buffer:
PBS, pH7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
4345
NCBI Official Name:
CD200 molecule
NCBI Official Symbol:
CD200
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
23.4 kDa
Protein Accession #:
AAH22522
Purity:
>98% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P41217

Documents