ProSci

Fetuin B Recombinant Protein

Product Code:
 
PSI-96-312
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-312-0.1mg0.1mg£597.00
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Further Information

Additional Names:
FETUB, Fetuin-B, 16G2, Gugu
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Fetuin-B (FETUB), a second member of the fetuin family in mammals, is also known as Fetuin-like protein IRL685, 16G2 and Gugu, which is expressed in liver and testis and contains 2 cystatin fetuin-B-type domains. FETUB is a protease inhibitor required for egg fertilization. FETUB is also required to prevent premature zona pellucida hardening before fertilization, probably by inhibiting the protease activity of ASTL, a protease that mediates the cleavage of ZP2 and triggers zona pellucida hardening (By similarity). As a liver-derived plasma protein, FETUB is essential for fertilization.
Background References:
  • Olivier E., et al., 2000, Biochem. J. 350:589-597.
  • Dietzel E., et al., 2013, Dev. Cell 25:106-112.
  • Muzny D.M., et al., 2006, Nature 440:1194-1198.
Buffer:
50 mM Tris, 150 mM NaCl,pH8.0
Fusion Tag:
His Tag
NCBI Gene ID #:
26998
NCBI Official Name:
fetuin B
NCBI Official Symbol:
FETUB
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
42.4 kDa
Protein Accession #:
AAH69670
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9UGM5

Documents