ProSci

Lipopolysaccharide Recombinant Protein

Product Code:
 
PSI-96-506
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Application:
 
Western Blot (WB)
Storage:
 
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
 

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PSI-96-506-0.1mg0.1mg£686.00
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Further Information

Additional Names:
Lambda Chain Binding Protein, Lambda Binding Protein, LBP
Application Note:
This recombinant protein can be used for WB. For research use only.
Background:
Lipopolysaccharide-binding protein (LBP),a member of the BPI/LBP/Plunc superfamily, BPI/LBP family, is detected in blood serum. LBP plays a role in the innate immune response. Alao,LBP can bind to the lipid A moiety of bacterial lipopolysaccharides (LPS), a glycolipid present in the outer membrane of all Gram-negative bacteria, and act as an affinity enhancer for CD14, facilitating its association with LPS. Furthermore, LBP is able to promote the release of cytokines in response to bacterial lipopolysaccharide.
Background References:
  • Schumann R.R., et al., 1990, Science 249:1429-1431.
  • Hubacek J.A., et al., 1997, Biochem. Biophys. Res. Commun. 236:427-430.
  • Eckert J.K., et al., 2013, Immunity 39:647-660.
Buffer:
PBS, pH 7.4
Fusion Tag:
His Tag
NCBI Gene ID #:
3929
NCBI Official Name:
lipopolysaccharide binding protein
NCBI Official Symbol:
LBP
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Predicted Molecular Weight:
52.8 kDa
Protein Accession #:
P18428
Purity:
>95% as determined by SDS-PAGE.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
P18428

Documents