AdipoGen Life Sciences

BRS-3 Agonist

Product Code:
 
AG-CR1-3607
Product Group:
 
Other Biochemicals
Regulatory Status:
 
RUO
Shipping:
 
-20°C
Storage:
 
-20°C
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Chemical Structure
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Chemical Structure

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AG-CR1-3607-C500500 ug£155.00
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Further Information

Alternate Names/Synonyms:
Bombesin Receptor Subtype-3 Agonist; Compound 5 {10,3}; (2E)-N-[2-(3,4-Dimethoxyphenyl)ethyl]-3-(2-furanyl)-2-propenamide
Appearance:
White solid.
CAS:
1426294-15-6
EClass:
32160000
Form (Short):
solid
Handling Advice:
Keep cool and dry.
InChi:
InChI=1S/C17H19NO4/c1-20-15-7-5-13(12-16(15)21-2)9-10-18-17(19)8-6-14-4-3-11-22-14/h3-8,11-12H,9-10H2,1-2H3,(H,18,19)/b8-6-
InChiKey:
RTMCVKRRGDEHTR-VURMDHGXSA-N
Long Description:
Chemical. CAS: 1426294-15-6. Formula: C17H19NO4. MW: 301.3. Bombesin receptor subtype-3 (BRS-3) agonist. Energy homeostasis regulator.
MDL:
N/A
Molecular Formula:
C17H19NO4
Molecular Weight:
301.3
Other data:
Bombesin receptor subtype-3 (BRS-3) is known as an orphan G-protein coupled receptor and belongs to the bombesin receptor family. BRS-3 receptor is expressed not only in brain but also in other peripheral organs such as intestine, liver, lung, testes and pancreas. Since BRS-3 deficient mice develop obesity and impaired glycemic regulation, ligands that modulate BRS-3 signaling are potential targets for diabetes and obesity treatments.
Package Type:
Vial
Product Description:
Bombesin receptor subtype-3 (BRS-3) agonist. Energy homeostasis regulator.
Purity:
>97% (NMR)
SMILES:
COC1=C(OC)C=C(CCNC(=O)C=CC2=CC=CO2)C=C1
Solubility Chemicals:
Soluble in DMSO or MeOH. Insoluble in water.
Transportation:
Non-hazardous
UNSPSC Category:
Biochemical Reagents
UNSPSC Number:
12352200
Use & Stability:
Stable for at least 2 years after receipt when stored at -20°C.

References

Column chromatography-free solution-phase synthesis of a natural piper-amide-like compound library: S. Kim, et al.; ACS Comb. Sci. 15, 208 (2013)