AdipoGen Life Sciences

Resistin (human) (rec.)

Product Code:
 
AG-40A-0010Y
Product Group:
 
Recombinant Proteins
Regulatory Status:
 
RUO
Target Species:
 
Human
Shipping:
 
Blue Ice
Storage:
 
+4°C (short term), -20°C (long term).
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Effect of Resistin (human) (rec.) (AG-40A-0010Y) on glucose uptake in L6 cells. Inhibition of insulin-stimulated glucose uptake in L6 skeletal muscle cells by resistin (as expected: 1?g/ml). Rat myoblasts (L6) were cultured and differentiated into myotub
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Effect of Resistin (human) (rec.) (AG-40A-0010Y) on glucose uptake in L6 cells. Inhibition of insulin-stimulated glucose uptake in L6 skeletal muscle cells by resistin (as expected: 1?g/ml). Rat myoblasts (L6) were cultured and differentiated into myotub

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AG-40A-0010Y-C01010 ug£200.00
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AG-40A-0010Y-C05050 ug£580.00
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Further Information

Alternate Names/Synonyms:
FIZZ3; Found in Inflammatory Zone 3; ADSF; Adipose Tissue-Specific Secretory Factor
Biological Activity:
Inhibits insulin-stimulated glucose uptake in L6 skeletal muscle cells.
Concentration:
After reconstitution:for 10µg size: 0.1mg/mlfor 50µg size: 1 mg/ml
EClass:
32160000
Endotoxin:
<0.01EU/µg purified protein (LAL test; Lonza).
Form (Short):
liquid
Formulation:
Lyophilized. Contains PBS.
Handling Advice:
After reconstitution, prepare aliquots and store at -20°C.Avoid freeze/thaw cycles.Centrifuge lyophilized vial before opening and reconstitution.PBS containing at least 0.1% BSA should be used for further dilutions.
Long Description:
Protein. Human resistin (aa 19-108) is fused at the N-terminus to a FLAG®-tag. Source: HEK 293 cells. Endotoxin content: <0.01EU/µg purified protein (LAL test; Lonza). Lyophilized. Contains PBS. Purity: >95% (SDS-PAGE). The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Molecular Weight:
~13kDa (SDS-PAGE)
NCBI, Uniprot Number:
Q9HD89
Package Type:
Plastic Vial
Product Description:
The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM; RELM-alpha/FIZZ 1 and RELM-beta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
Purity:
>95% (SDS-PAGE)
Sequence:
Human resistin (aa 19-108) is fused at the N-terminus to a FLAG®-tag.
Source / Host:
HEK 293 cells
TAGs:
FLAG
Transportation:
Non-hazardous
UNSPSC Category:
Other Proteins
UNSPSC Number:
12352202
Use & Stability:
Stable for at least 6 months after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C.

References

Expression of resistin in the prostate and its stimulatory effect on prostate cancer cell proliferation: H.J. Kim, et al.; BJU Int. 108: 1464 (2010)