Further Information
LMNB1, lamin B1, ADLD, LMN, LMN2, LMNB, MGC111419, OTTHUMP00000159218, lamin-B1
Peptide ELISA: antibody detection limit dilution 1:4000.Western Blot:Approx 70kDa band observed in nuclear lysates of cell lines HeLa and Jurkat and approx. 70-75kDa in Mouse Liver lysates (calculated MW of 66.4kDa according to Human NP_005564.1 and 66.8kDa according to Mouse NP_034851.2) Recommended concentration: 1-3ug/ml.
- Schuster J, Sundblom J, Thuresson AC, Hassin-Baer S, Klopstock T, Dichgans M, Cohen OS, Raininko R, Melberg A, Dahl N.Genomic duplications mediate overexpression of lamin B1 in adult-onset autosomal dominant leukodystrophy (ADLD) with autonomic symptoms.
Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Aliquot and store at -20?C. Minimize freezing and thawing.
500 ug/mL
Unconjugated
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Expected Species Reactivity based on sequence homology: Dog, Pig, Cow
The immunogen for this antibody is: C-DVKVILKNSQGE
4001
lamin B1
LMNB1
Homo sapiens
Liquid
PREDICTED MOLECULAR WEIGHT:
Approx 70kDa
NP_005564.1, NP_001185486.1
125953
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Neuroscience, Obesity, Signal Transduction
This antibody is expected to recognize both reported isoforms (NP_005564.1; NP_001185486.1).
P20700