ProSci

PIDD Antibody [Lise-1]

Product Code:
 
PSI-36-150
Product Group:
 
Primary Antibodies
Supplier:
 
ProSci
Host Type:
 
Mouse
Antibody Isotype:
 
IgG2b, kappa
Antibody Clonality:
 
Monoclonal
Antibody Clone:
 
Lise-1
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Application:
 
Western Blot (WB)
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C.
 

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PSI-36-150-100ug100ug£686.00
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Further Information

Additional Names:
p53-induced Protein with a Death Domain; Leucine-rich Repeat and Death Domain-containing Protein; Lrdd
Application Note:
Western Blot: (1:1,000).
Background:
PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
Buffer:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
Concentration:
1 mg/ml
Conjugate:
Unconjugated
DISCLAIMER:
Optimal dilutions/concentrations should be determined by the end user. The information provided is a guideline for product use. This product is for research use only.
Immunogen:
Mouse PIDD (Death Domain).
NCBI Gene ID #:
57913
NCBI Official Name:
p53 induced death domain protein 1
NCBI Official Symbol:
Pidd1
NCBI Organism:
Mus musculus
Physical State:
Liquid
Protein Accession #:
81868332
Protein GI Number:
Q9ERV7
Purification:
>95% (SDS-PAGE)
Research Area:
Apoptosis,Cancer,Innate Immunity
SPECIFICITY:
Recognizes mouse PIDD.
Swissprot #:
Q9ERV7
User NOte:
Optimal dilutions for each application to be determined by the researcher.