ProSci

ST2 Recombinant Protein

Product Code:
 
PSI-90-054
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-054-50ug50ug£801.00
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Further Information

Additional Names:
Interleukin-1 Receptor-like 1, IL-1 Receptor-like 1, IL1RL1, IL-33 Receptor, Interleukin-33 Receptor
Application Note:
This recombinant proteins is for research use only.
Background:
The ST2 (Interleukin-1 receptor-like 1; Interleukin-33 receptor) gene was originally identified as a gene induced by serum or oncogene expression in fibroblasts. The gene produces a shorter soluble secreted form (ST2) and a longer, transmembrane form (ST2L) by alternative splicing. Soluble ST2 has been shown to downregulate the expression of TLR1 and TLR4. ST2L negatively regulates TLR4 signaling and induces endotoxin tolerance, and enhances Th2 responses. IL-33 is the specific ligand for ST2L.
Biological Activity:
Interacts with human IL-33.
Buffer:
0.2um-filtered solution in PBS, pH 7.2.
Concentration:
~0.5mg/ml
Fusion Tag:
Fc Tag
NCBI Gene ID #:
9173
NCBI Official Name:
interleukin 1 receptor like 1
NCBI Official Symbol:
IL1RL1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
Q01638
Protein GI Number:
116242527
Purity:
>90% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
Q9Y5C1

Documents