ProSci

LAG-3 Recombinant Protein

Product Code:
 
PSI-90-241
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Monkey
  • Mouse
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-241-50ug50ug£657.00
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Further Information

Additional Names:
Lymphocyte Activation Gene-3, FDC Protein, CD223
Application Note:
This recombinant proteins is for research use only.
Background:
Lymphocyte activation gene 3 (LAG-3; CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
Biological Activity:
Inhibits binding of MAb to LAG-3 (human) to LAG-3. Induces maturation of human dendritic cells.
Buffer:
In PBS.
Concentration:
0.5 mg/ml
Fusion Tag:
Fc Tag
NCBI Gene ID #:
3902
NCBI Official Name:
lymphocyte activating 3
NCBI Official Symbol:
LAG3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Protein Accession #:
P18627
Protein GI Number:
251757512
Purity:
>99% (SDS-PAGE).

Endotoxin level is less than 0.1EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
O95631

Documents