ProSci

OX40 Recombinant Protein

Product Code:
 
PSI-90-227
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
  • Human
  • Mouse
Storage:
 
Stable for at least 6 months after receipt when stored at -20˚C.
 

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PSI-90-227-50ug50ug£609.00
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Further Information

Additional Names:
TNFRSF 4, Tumor Necrosis Factor Receptor Superfamily Member 4, CD134
Application Note:
This recombinant proteins is for research use only.
Background:
OX40 binds to receptors on T-cells, preventing them from dying and subsequently increasing cytokine production. OX40 has a critical role in the maintenance of an immune response. OX40:Fc was shown to prevent OX40 from reaching the T-cell receptors, thus reducing the T-cell response. Experiments in mice have demonstrated that OX40:Fc can reduce the symptoms associated with the cytokine storm (an immune overreaction) while allowing the immune system to fight off the virus successfully.
Biological Activity:
Blocks T cell proliferation induced by CD134L.
Buffer:
Contains PBS. Reconstitute with 50 μl sterile water.
Concentration:
1mg/ml after reconstitution.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
7293
NCBI Official Name:
tumor necrosis factor receptor superfamily member 4
NCBI Official Symbol:
TNFRSF4
NCBI Organism:
Homo sapiens
Physical State:
Lyophilized
Protein Accession #:
P43489
Protein GI Number:
1171933
Purity:
>95% (SDS-PAGE).

Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
HEK293 cells
Swissprot #:
O75888

Documents