ProSci

IL-6R Recombinant Protein

Product Code:
 
PSI-90-488
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
Stable for at least 1 year after receipt when stored at -20˚C. Working aliquots are stable for up to 3 months when stored at -20˚C.
 

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PSI-90-488-50ug50ug£626.00
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Further Information

Additional Names:
Interleukin-6 Receptor Subunit alpha, IL6RA, CD126
Application Note:
This recombinant proteins is for research use only.
Background:
Interleukin 6 receptor (IL-6R; CD126) is a type I cytokine receptor, which is a protein complex consisting of an IL-6 receptor subunit (IL-6R) and interleukin 6 signal transducer glycoprotein 130 (gp130). It is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in immune response. Dysregulated production of IL-6 and IL-6R are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer.
Biological Activity:
Measured by its binding ability in a functional ELISA.
Buffer:
Lyophilized from 0.2um-filtered solution in PBS. Reconstitute at 100 μg/ml in sterile PBS.
Fusion Tag:
Fc Tag
NCBI Gene ID #:
16194
NCBI Official Name:
interleukin 6 receptor, alpha
NCBI Official Symbol:
Il6ra
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Protein Accession #:
CAA37810
Protein GI Number:
52693
Purity:
>98% (SDS-PAGE).

Endotoxin level is less than 0.06EU/ μg protein (LAL test; Lonza).
Recombinant Protein Sequence:
Thr32-Gly402
Source:
CHO cells
Swissprot #:
P36941

Documents