ProSci

4-1BB Recombinant Protein

Product Code:
 
PSI-92-374
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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CodeSizePrice
PSI-92-374-0.05mg0.05mg£613.00
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Further Information

Additional Names:
Secreted CD137 antigen , Tumor necrosis factor receptor superfamily member 9 , Tnfrsf9, TNFRSF9, CD137
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells and the cross-linking of this protein can enhance T cell proliferation, IL-2 secretion survival and cytolytic activity. Further, it can enhance immune activity to eliminate tumors in mice.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM PB,150mM NaCl,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-Fc tag
NCBI Gene ID #:
21942
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 9
NCBI Official Symbol:
Tnfrsf9
NCBI Organism:
Mus musculus
Physical State:
Liquid
Predicted Molecular Weight:
44.7 kD
Protein Accession #:
P20334
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
P20334

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