ProSci

Uridine Phosphorylase 1 Recombinant Protein

Product Code:
 
PSI-92-122
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-92-122-0.05mg0.05mg£673.00
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Further Information

Additional Names:
UPP1 Protein, Uridine Phosphorylase 1, UPP1
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Uridinephosphorylase 1 (UPP1) is a member of the family of pentosyltransferase. UPP1 catalyses the reversible phosphorolysis of uridine to uracil. The expression levels and the enzymatic activity of UPP1 are higher in human solid tumors than in adjacent normal tissues. The high level of UPP1 expression in some tumors makes it a potential prognosticfactor for some cancers, such as oral squamous cell carcinoma. UPP1 is important for the homeostatic regulation of intracellular and plasma uridine concentratios. UPP1 plays an important role in the pyrimidine salvage pathway through its catalysis of the reversible phosphorolysis of uridine to uracil.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM Tris, 200mM NaCl, 1mM DTT, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
7378
NCBI Official Name:
uridine phosphorylase 1
NCBI Official Symbol:
UPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
21.3 kD
Protein Accession #:
Q86Y75
Protein GI Number:
929654682
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q86Y75

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