ProSci

GITR Recombinant Protein

Product Code:
 
PSI-91-947
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Mouse
Storage:
 
Lyophilized protein should be stored at -20˚C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚C for 3 months.
 

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PSI-91-947-0.05mg0.05mg£597.00
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This product comes from: United States.
Typical lead time: 14-21 working days.
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Further Information

Additional Names:
Tumor necrosis factor receptor superfamily member 18, Glucocorticoid-induced TNFR-related protein, Tnfrsf18, AITR, CD357, GITR-D
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA, isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and TRAF3, but not TRAF5 and TRAF6 and binds through its C-terminus to SIVA1/SIVA.It preferentially expressed in activated T lymphocytes and up-regulated in peripherical mononuclear cells after antigen stimulation/lymphocyte activation.
Buffer:
Lyophilized from a 0.2 um filtered solution of PBS,pH7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml. Dissolve the lyophilized protein in ddH2O.
Fusion Tag:
C-Fc-6 His tag
NCBI Gene ID #:
21936
NCBI Official Name:
tumor necrosis factor receptor superfamily, member 18
NCBI Official Symbol:
Tnfrsf18
NCBI Organism:
Mus musculus
Physical State:
Lyophilized
Predicted Molecular Weight:
42.3 kD
Protein Accession #:
O35714
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
O35714

Documents