ProSci

Sentrin-Specific Protease 7 Recombinant Protein

Product Code:
 
PSI-91-151
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-151-0.05mg0.05mg£673.00
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Further Information

Additional Names:
Sentrin-Specific Protease 7, SUMO-1-Specific Protease 2, Sentrin/SUMO-Specific Protease SENP7, SENP7, KIAA1707, SSP2, SUSP2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPase-activating protein 1) but had limited activity against SUMO-1-modified RanGAP1.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM HEPES, 5% Glycerol, pH 7.4. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
57337
NCBI Official Name:
SUMO1/sentrin specific peptidase 7
NCBI Official Symbol:
SENP7
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
27.3 kD
Protein Accession #:
Q9BQF6
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
Q9BQF6

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