ProSci

Aldehyde dehydrogenase 1-A3 Recombinant Protein

Product Code:
 
PSI-92-704
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-92-704-0.05mg0.05mg£613.00
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Further Information

Additional Names:
Aldehyde dehydrogenase family 1 member A3, ALDH1A3, Aldehyde dehydrogenase 6, Retinaldehyde dehydrogenase 3, RALDH-3, ALDH6
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Aldehyde dehydrogenase 1 family member A3 (ALDH1A3), also known as retinaldehyde dehydrogenase 3 (RALDH3), is a member of the aldehyde dehydrogenase family known to metabolize a wide variety of aldehydes. ALDH1A3 specifically oxidizes retinal to retinoic acid (RA) and is differentially expressed in developing embryonic tissues and adult organs. The RA produced by ALDH1A3 in rodents contributes to the development of skin and hair follicles, brain, tooth buds, lungs, olfactory bulbs, kidneys, eyes, skeletal muscle and seminal vesicles. In recent research, ALDH1A3 could be as a marker of cancer stem cell to predict metastasis or clinical prognosis in many cancers.
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl,150mMNaCl, pH7.5,20% Glycerol.
Fusion Tag:
N-6 His tag
NCBI Gene ID #:
220
NCBI Official Name:
aldehyde dehydrogenase 1 family member A3
NCBI Official Symbol:
ALDH1A3
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
57.5 kD
Protein Accession #:
P47895
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
E. coli
Swissprot #:
P47895

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