ProSci

MINPP1 Recombinant Protein

Product Code:
 
PSI-91-475
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-475-0.05mg0.05mg£673.00
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Further Information

Additional Names:
Multiple Inositol Polyphosphate Phosphatase 1, 2, 3-Bisphosphoglycerate 3-Phosphatase, 3-BPG Phosphatase, Inositol (1, 3, 4, 5)-Tetrakisphosphate 3-Phosphatase, Ins(1, 5)P(4) 3-Phosphatase, MINPP1, MIPP
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Multiple Inositol Polyphosphate Phosphatase 1/MINPP1 is an enzyme that removes 3-phosphate from inositol phosphate substrates. MINPP1 also converts 2,3 bisphosphoglycerate (2,3-BPG) to 2-phosphoglycerate. MINPP1 is synthesized as a 487 amino acid precursor that contains an 30 amino acid signal peptide and a 457 amino aicd mature chain. MINPP1 is widely expressed with the highest levels found in kidney, liver and placenta. It acts as a phosphoinositide 5- and phosphoinositide 6-phosphatase and regulates cellular levels of inositol pentakisphosphate (InsP5) and inositol hexakisphosphate (InsP6). MINPP1 may play a role in bone development (endochondral ossification).
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 7.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
9562
NCBI Official Name:
multiple inositol-polyphosphate phosphatase 1
NCBI Official Symbol:
MINPP1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
53.14 kD
Protein Accession #:
Q9UNW1
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q9UNW1

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