ProSci

POMGNT1 Recombinant Protein

Product Code:
 
PSI-91-563
Product Group:
 
Recombinant Proteins
Supplier:
 
ProSci
Regulatory Status:
 
RUO
Target Species:
 
Human
Storage:
 
Store at -20˚C, stable for 6 months after receipt.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
 

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PSI-91-563-0.05mg0.05mg£883.00
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Further Information

Additional Names:
Protein O-Linked-Mannose Beta-1, 2-N-Acetylglucosaminyltransferase 1, POMGnT1, UDP-GlcNAc:Alpha-D-Mannoside Beta-1, 2-N-Acetylglucosaminyltransferase I.2, GnT I.2, MGAT1.2
Application Note:
This recombinant protein can be used for biological assays. For research use only.
Background:
Protein O-Linked-Mannose beta -1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystrophy-dystroglycanopathy congenital with brain and eye anomalies type A3 (MDDGA3).
Buffer:
Supplied as a 0.2 um filtered solution of 20mM TrisHCl, 150mM NaCl, 10% Glycerol, pH 8.5. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Fusion Tag:
C-6 His tag
NCBI Gene ID #:
55624
NCBI Official Name:
protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-)
NCBI Official Symbol:
POMGNT1
NCBI Organism:
Homo sapiens
Physical State:
Liquid
Predicted Molecular Weight:
69.3 kD
Protein Accession #:
Q8WZA1
Protein GI Number:
158257574
Purity:
Greater than 95% as determined by reducing SDS-PAGE.
Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Recombinant Protein Sequence:
Thr32-Gly402
Source:
Human Cells
Swissprot #:
Q8WZA1

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